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Description

Abnormalities in the expression or function of FOXO6 have been identified as a pathophysiological basis for the development of fasting hyperglycemia and hyperlipidemia, which are serious metabolic complications in diabetic patients

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This suppression establishes a self-reinforcing cycle where inflammation exacerbates IR by diminishing the regulatory capacity of FGF-21 [218]

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The issue of regression is of clinical importance

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