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CrossRef ATF4 in cardiovascular diseases: an emerging therapeutic target Luning Qin, Ruolan Chen, Chao Huang, Xuezhe Wang, Qinghang Song, Zhaoqing Li, Xiaojian Xu, Zhijun Liu, Banghui Wang, Bing Li, Xian-Ming Chu Biochemical Pharmacology.2026

An evidence-controlled analysis Antonietta Gerarda Gravina, Raffaele Pellegrino, Marina Cipullo, Giovanna Palladino, Giuseppe Imperio, Andrea Ventura, Salvatore Auletta, Paola Ciamarra, Alessandro Federico World Journal of Gastroenterology .2024

9.3 Course, prognosis, cause of death Course : acute overdose results in seizures associated with metabolic acidosis, coma and respiratory distress

Eating smaller meals, avoiding high-fat foods, staying hydrated, and dosing escalation protocols all reduce nausea rates in clinical trials and practice