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Skin Pigmentation and Glutathione Melanogenesis begins with the conversion of L-tyrosine to DOPA-quinone under the effect of tyrosinase enzyme (Figure 1)

10.1016/j.pain.2013.07.032 73 JanesK.LittleJ

The resulting duplex DNAs were purified by phenolchloroform extraction and ethanol precipitation, and transcribed into mRNAs for the next round of selection