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Therefore, future studies could combine metabolic therapy with radiotherapy, chemotherapy, targeted therapy or immunotherapy to counteract tumor heterogeneity and improve the prognosis of patients with TNBC (119)

31 Oral use of ALC has been shown to improve neuropathic pain in DPN, 43,46,47 with some studies demonstrating its efficacy for antiretroviral toxic neuropathy

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showed that MMI + antioxidants (83 ug selenomethionine + 17 ug Se yeast + vitamin D) treatment for 6 months improved thyroid activity more effectively than MMI use that alone (20)

Clinical trials in cancer patients with rapalogs, particularly as monotherapies, revealed only modest efficacy, with limited and inconsistent therapeutic responses across tumor types