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[DOI] [PubMed] [Google Scholar] Duan W

IBRO Neurosci

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Methylmercury induces Mitochondria- and Endoplasmic reticulum Stress-Dependent pancreatic beta-Cell apoptosis via an oxidative Stress-Mediated JNK signaling pathway

If the 4 mg maintenance arm proves non-inferior for weight maintenance in Phase 3, researchers may be able to titrate up to a high working dose during the active weight-loss phase, then step back down to a lower 4 mg maintenance dose for the long stabilization phase