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Alterations in the GABA-switch (from excitatory to inhibitory) can cause a delay in when the developing neural circuits reach functional maturity, with consequences for network activity

Reductions in the total rate of apoptosis in GCs were also observed for QUE ( p = 0.0187 ), CAR ( p = 0.0234 ), SFN ( p = 0.0165 ), and MIX ( p = 0.0228 ) compared to the control group under HS conditions (Figure 1D

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The CRISPR-Cas12 system found in prokaryotes is thought to have evolved from TnpB by adding additional domains, as the original TnpBs only contains a basic domain that carries out the function of the CRISPR-Cas12 family

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