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The eyes can be affected as well, leading to a condition known as Graves ophthalmopathy, which manifests with bulging eyes, double vision, and eye irritation

G.LevineS.FelsensteinD.BatemanL.et al

FIGURE 4 3.6 KEGG pathway analysis of the significantly differential metabolites According to the annotation results, the significantly differential metabolites were mainly involved in amino acid metabolism, carbohydrate metabolism, lipid metabolism, membrane transport and translation (Figure 5A)