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Of mice and men: models and mechanisms of diabetic cardiomyopathy

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potentially fatal disturbances of cardiac conduction (widening of QRS), arrhythmias & seizures due to Na channel block (cardiac & CNS) Pharmacokinetics: PO, metabolized in the liver (P450 - 2D6)

This lack of subcellular localization is also a limitation of spectroscopic measurements, such as those using fluorescent tags or inherent fluorescence

In conclusion, while preliminary results of acupuncture are encouraging, especially in terms of antibody reduction and select QoL improvements, rigorous, larger-scale, and theory-driven RCTs are needed to determine its definitive role in the management of euthyroid HT with persistent symptoms