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Others require medical treatment such as injections or guided procedures

Arabidopsis mutants lacking cy- tosolic isocitrate dehydrogenase (icdh), an NADP- linked enzyme, have very similar NADPH-NADP+ and GSH-GSSG ratios to the wild type (Mhamdi et al., 2010b)

These observations may be of great clinical importance

doi: 10.1126/science.1166296 127 KhoSBarberBEJoharEAndriesBPoespoprodjoJRKenangalemEet al

There is accumulating evidence that almost all such gene families have been rapidly evolving through complex structural variations [52], creating lineage-specific repertoires of functional diversity [35, 53]