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Prior to being used as a clinical application, MSM primarily served as a high-temperature, polar, aprotic, commercial solvent, as did its parent compound, dimethyl sulfoxide (DMSO) [2]

To understand why senescent cells are more prone than normal counterparts to undergo ferroptosis on GPX4 inhibition, we used fluorescence probes to analyse ROS, levels of Fe 2+ and lipid oxidation in senescent cells