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By modulating inflammatory pathways, glutathione helps alleviate liver inflammation, reducing the risk of disease progression

In addition, cotreatment of docetaxel-resistant NSCLC with docetaxel plus R162 inhibited cancer cell growth and metastasis both in vitro and in xenograft mouse models, again suggesting that combination therapy with anticancer drugs plus a GLUD1 inhibitor is an effective cancer treatment 23

However, in individuals without a deficiency, its effect appears limited to supporting normal keratin infrastructure rather than driving excessive follicular stimulation