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Hits that fulfilled the following requirements were designated as significant events at each timepoint: P adj 0.05 and appeared under at least two pairwise comparisons (that is, T-REX versus two different controls) out of the three (Supplementary Data 4)

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Also, supplementation with Lcysteine (LC), a rate-limiting precursor of GSH 5 , boosts the levels of GSH, reduces oxidative stress, and improves circulating 25(OH)VD 3 levels 7,8,9,10,11,12

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Nat Rev Mol Cell Biol 8:813824 Duggett NA et al (2016) Oxidative stress in the development, maintenance and resolution of paclitaxel-induced painful neuropathy