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The dissociation constant ( K D ) values for Cu(II) in NTS of HSA (Asp-Ala-His) and of bovine serum albumin (Asp-Thr-His), have been determined by a variety of methods such as potentiometric titration, equilibrium dialysis, ultrafiltration, isothermal titration calorimetry, Cu(II) electrode and several spectroscopic methods, including EPR 27

Additionally, there is evidence showing that individuals with schizophrenia have oxidative stress

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Administered at 50 mg/kg, three times weekly for 3 months, ERD upregulated GPX4 and downregulated ACSL4 and TfR1, reducing oxidative stress and iron accumulation