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Gel packs and insulated containers maintain sub-zero temperatures for 2448 hours under optimal conditions, but delays, ambient temperatures above 30C, or improper packing can result in partial thawing

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It enables us to localise pain, to measure its duration, and to verify the existence of the characteristic refractory period observed in TN.5 We must also assess any accompanying symptoms, including autonomic signs (conjunctival injection, tearing, rhinorrhoea), which are less pronounced and briefer than those observed in short-duration trigeminal autonomic cephalalgias, such as short-lasting unilateral neuralgiform headache attacks (SUNCT) and short-lasting unilateral neuralgiform headache attacks with cranial autonomic symptoms (SUNA).39,40 In the medical history interview, painful trigeminal neuropathy is described as continuous or near-continuous pain, without the predominance of painful paroxysms observed in TN

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