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Fibroblast cultures are commonly used to measure transcriptional responses involving matrix-associated proteins, growth signaling regulators, and stress-response pathways

Likewise in our previous studies of glaucoma, we have observed metabolic deficiency in the DBA/2J optic nerve that coincides with an early period of degeneration [69]

King, M.-J., Smythe, J

Journal of Clinical Investigation, 97(8), 1941-1946

In particular, astrocytes, as the cells supporting neuronal function, seem to be of great importance for our understanding of underlying disease mechanisms (5)