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Synthetic lethality by targeting glutathione and pyrimidylate kinases in human CML-BC cell lines Finally, we further used several human blast-crisis CML cell lines, including K562, KOPM28, and TCCS, to verify the relationship between ATF4, GSH, and replication stress

Several types of allelic variation have been identified within classes, with GSTM1 -null, GSTT1 -null and GSTP1-Ile105/Ile105 conferring impaired catalytic activity

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Transfection of HT-29 colon cancer cells with let-7-1 suppressed COP9 signalosome expression and increased mitomycin C activity [121]