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Osborne, MD, PhD, a cardiologist who specializes in hypertension and preventive cardiology and medical director of State of the Heart Cardiology in Southlake, Texas

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Although energy metabolism status can also regulate intracellular ROS levels (e.g., glucose deprivation leads to a marked increase in cellular ROS) [53,54,55,56], our study demonstrated that supplementation with energy substrates such as sodium pyruvate in GGCT-knockdown cell models did not induce significant alterations in intracellular ROS levels

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