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[DOI] [PMC free article] [PubMed] [Google Scholar] 71.Syed D.N., Adhami V.M., Khan M.I., Mukhtar H

Alpha-1-antitrypsin (A1AT), beyond its role as a serine protease inhibitor, exhibits significant antioxidative properties, playing a crucial role in the neutralization of reactive oxygen species (ROS) through sophisticated mechanisms

338 However, in heart failure, DEAD-box helicase 17 and B-cell lymphoma 6 are downregulated, which would reverse the inhibition of Drp1 and promote mitochondrial fission