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They are a sign that the drug is working

Mechanisms Angiogenesis, actin regulation, neuroprotection, NF-kB modulation and collagen synthesis complementary targets

10.1177/17474930221144911 53 MengH.XiaoL.ZhangC.ZhangT.XiaD.DongW

An important characteristic of CIPp-18 which played significant role in its PDT efficacy was its amphiphilic nature and ability to disaggregate in media containing 10% serum [37]