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Following separated 1:1 PSM (all 472 pairs), the incidence of HCC in BSV users (n=6, 4.4 per 1000 PYs) was similar to that in TAF users (n=12, 8.6 per 1000 PYs, log-rank P =0.782, aHR 1.167, 95% CI 0.3923.471), however, significantly lower than in ETV (n=27, 15.2 per 1000 PYs, log-rank P=0.025, aHR 2.978, 95% CI 1.024 8.659, E-value 5.404), and TDF users (n=27, 16.6 per 1000 PYs, log-rank P=0.025, aHR 3.000, 95% CI 1.0908.254, E-value 5.449)

The dominant-negative H-RAS (S17N) further hinders the SNX27b-dependent decrease in surface expression of GIRK2c/GIRK3 channels

The moderate degree of this correlation was attributed to inherent variability of each measure, intra-session variability in the BOLD response itself, possible learning effects and/or fatigue

Availability of data and materials The raw data is provided in a supplementary file

Observations on repeated biopsies in sixteen patients