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It was a mess, says Harris Huberman, a pediatrician at Downstate Health Sciences University, who is collaborating on that study

Elevated circulating trimethylamine N-Oxide levels contribute to endothelial dysfunction in aged rats through vascular inflammation and oxidative stress

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Intriguingly, the phenotypes obtained by most investigators using iPSC-derived neurons from donors with SCZ show reduced dendritic spine and reduced synaptic functions, hinting to a neurodevelopment-related impairment (Figure 1)

Hum Genet 1999;105:157-161