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Glycogenic hepatopathy: an underrecognized hepatic complication of diabetes mellitus

It may occur sporadically, for example after an insect bite, or persist in a chronic context, such as in the case of eczema

It has been demonstrated in mice with adipocytes deficient in mitochondrial transcription factor A that isolated mitochondrial dysfunction in adipose tissue can cause lipodystrophy and lead to MS and chronic inflammation (Vernochet et al., 2014)