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Description

This total iron requirement reflects the amount of iron needed to restore hemoglobin concentration to normal or near normal levels plus an additional allowance to provide adequate replenishment of iron stores in most individuals with moderately or severely reduced levels of hemoglobin

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In this kind of apoptosis, Bax activation and translocation leads to status alterations of mitochondrial permeability transition pores, facilitating depolarization of mitochondrial membrane potential and subsequent release of cytochrome c and other apoptosis-promoting proteins to cytosol (Kim et al., 2021