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In vivo , treatment with AST alleviated motor impairments and mitigated the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) of C57BL/6J mice

Derived from epithalamin research, it has been investigated in models of telomere biology and pineal gland signaling

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(2014) found that DSIP could protect neurons from oxidative stress, suggesting potential applications in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's disease