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J.PosthumusM.CollinsM.et al (2016)

See the two charts below: RETURN TO TOP October 14, 2015: Cardiologists focus on bionic fixes to the leaking mitral valve Four man-made devices are in the works Since the first realization that some purebred dogs, particularly cavalier King Charles spaniels, regularly develop mitral valve disease, veterinary cardiologists have dealt with MVD-caused congestive heart failure by trying to "manage" its consequences with drugs