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"Depot These are preparations which are administered once with doses that is designed to be released at programmed release for a desired period of time.Usually they are administered as implants, they may be formulated with biodegradable or non biodegradable polymers

Free Radical Res Commun (1991) 12-13 Pt 1:1315

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Additionally, GGCT knockdown concomitantly reduced 5- oxoproline (5-OP) levels in MHCC97H cells, consistent with 5-OP being the direct enzymatic product of GGCT activity, and exogenous 5-OP rescued proliferation under Gln-deprived conditions (Fig