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M1 macrophage exosomes engineered to foster M1 polarization and target the IL-4 receptor inhibit tumor growth by reprogramming tumor-associated macrophages into M1-like macrophages

Indeed, sulfasalazine (which inhibits SLC7A11) effectively suppresses the proliferation of glutamine-depleted TNBC in vitro and in vivo 60

A 2018 randomized controlled trial published in the European Journal of Clinical Nutrition tested this exact regimen in 48 participants consuming five standard drinks over four hours

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