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Its worth noting that the cocrystal structure of compound 16, when bound to SjGST, clearly shows that its binding mode considerably overlaps with IBZGSH at the H-site, thus significantly differing from known GSH-like compounds

Meanwhile, the content of total NO was analyzed through determining nitrate and nitrite with the Total Nitric Oxide assay kit (Beyotime, Haimen, China) according to the manufacturers protocols

Alkaloids are a class of nitrogen-containing organic compounds known for their diverse biological activities and significant medicinal value

At present, only a small minority of patients referred for suspected MCAS are ultimately diagnosed with the condition, underscoring the need for allergists to better communicate with the public and other medical professionals about which clinical presentations are consistent with MCAS and which ones are clearly not [19, 95]

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age