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Migliavacca Center for Liver Disease, Department of Pathophysiology and Transplantation, University of Milan, (3)Clicon S.r.l

& Fernandes, S

Improved public health arises through better health of every individual

The first auto-Abs to be identified in RA were shown to bind the Fc fragment of IgG, resulting in circulating ICs that deposit in the cartilage and synovium and cause immune activation and chronic inflammation [205]