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Instead, laboratory data must be interpreted within the broader clinical context including symptom patterns, exposure history, inflammatory markers, and overall regulatory stability

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On the other hand, in the amyloidogenic pathway, APP at the N-terminal part of the A domain is cleaved by -site APP cleaving enzyme 1 (formerly known as -secretase) (BACE-1), resulting in release of extracellular soluble fragments of sAPP and a membrane bound C99 or -CTF [129, 130]

Glutathione is a naturally occurring antioxidant produced by the body that helps protect cells from oxidative stress and supports normal detoxification

LIF shares glycoprotein 130 (gp130) with other IL-6 cytokine family members.53 LIF mainly modulates neuronal activity such as glial cell activity, the inflammatory process, transcription pathways, and neurogenesis.545556 An appropriate amount of LIF is essential for normal neuronal function