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In a recent study, intraperitoneal injection of liproxstatin-1 (Lip-1, a ferroptosis inhibitor) in rats reduced iron content and lipid peroxidation in spinal cord tissue, alleviating CCI-induced mechanical and thermal nociceptive abnormalities ( Table 1 ) ( Figure 5 In clinical treatment, the most ordinary drug used to treat MS is glucocorticoids (GC) (123)