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Nat Rev Immunol 9:778788 Pasparakis M (2012) Role of NF-kappaB in epithelial biology

Subcutaneous injection is the only route that achieves reproducible systemic exposure

Strategies aimed at modulating the labile iron pool, enhancing GPX4 activity, or using ferroptosis inhibitors may provide novel means to mitigate ischemia-reperfusion injury and improve graft outcomes