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The RF model consistently achieved an average test Accuracy of 1.0 and an F1-score of 1.0 across the folds (Supplementary Table 2)

ROS can increase kinase activity, including JNK, by oxidizing cysteine residues on phosphatases, that restrict kinase activity or on other proteins that keep kinases inactive in non-stressed cells (Averill-Bates, 2024