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Additionally, they are not easy to manipulate during transport and inappropriate copper transport may lead to tissue-specific issues (25), thus, further study is required to improve the function of these carriers

These antigens are subsequently captured by DCs, processed, and presented via MHC molecules to naive T cells, leading to the activation of new T-cell clones against different tumor epitopes

6, excessive iodine intake is the most common environmental factor known to cause thyroid autoimmunity

doi:10.1210/jc.2018-00070 Rodbard HW, Lingvay I, Reed J, et al