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Homocysteine is an amino acid that builds up in the blood when methylation isn't working well

Clin Pharmacokinet (2012) 51(9):55372

GHK prevented an increase in MCP-1 and nitrotyrosine levels in the hippocampus of sleepdeprived mice suggesting that inflammatory and reactive nitrogen/oxygen species activity could be therapeutic targets for learning impairment associated with short-term sleep deprivation