hypothesis glutathione persister cells Mechanism of Drug Tolerant Cancer Cells: The Landscape and Clinical Implication for Therapy Targeted therapy for drug-tolerant persister
Targeted therapy for drug tolerant persister cells after imatinib treatment for gastrointestinal stromal tumours British Journal of Cancer Frontiers Exogenous cystine increases susceptibility of drug resistant Salmonella to gentamicin by promoting oxidation of glutathione metabolism and imbalance of intracellular redox levels A host directed adjuvant sensitizes intracellular bacterial persisters to antibiotics Nature Microbiology Drug tolerant persister cancer cells are vulnerable to GPX4 inhibition Nature Targeting of vulnerabilities of drug tolerant persisters identified through functional genetics delays tumor relapse: Cell Reports Medicine
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