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Mant, T.G.K

adults found that those consuming around 400-550mg/day of choline had a 28% lower risk of stroke, while those above 550mg/day had a 46% lower risk compared to people with very low intake.39 One last point on choline and cardiovascular health: some research has raised questions about trimethylamine-N-oxide (TMAO), a compound produced when gut bacteria metabolize choline (and also carnitine from red meat)

Vegans often have lower carnitine intake from diet, so supplementation can be useful

A prolonged inflammatory state can also promote he progression of atherosclerosis via promoting cholesterol deposition and damaging artery walls (122)

N-heterocyclic carbene catalyzed reaction of enals and 1,2-dicarbonyl compounds: stereoselective synthesis of spiro gamma-butyrolactones