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The coadministration of NAC and DFP attenuated iron accumulation and mitochondrial dysfunction, and improved synaptic plasticity and cognition in iron-fed rats (234)

Adverse effects include gastrointestinal symptoms and arrhythmias such as VPBs, VT, APBs, atrial tachycardia, and varying degrees of AV block in patients with structural heart disease or electrolyte disturbances (56)(58)

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