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doi: 10.3325/cmj.2022.63.389 135

Impairment of vitamin B 12 absorption can cause megaloblastic anemia and neurologic disorders in deficient subjects

Nutrition, 32(1), 6672

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In a pre- and post-natal study in rats administered subcutaneous doses of 0.02, 0.10, or 0.25 mg/kg tirzepatide twice weekly from implantation through lactation, F1 pups from F0 maternal rats given 0.25 mg/kg tirzepatide had statistically significant lower mean body weight when compared to controls from post-natal day 7 through post-natal day 126 for males and post-natal day 56 for females