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The year 1901 was also an important moment for chemists Emil Fischer and Ernest Fourneau, who carried out the first successful peptide synthesis, thus creating the first peptide

doi: 10.3390/toxics12050318

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J Pharmacol Exp Ther 241:527533 Roberts DW, Bucci TJ, Benson RW, Warbritton AR, McRae TA, Pumford NR, Hinson JA (1991) Immunohistochemical localization and quantification of the 3-(Cystein- S -yl)-acetaminophen protein adduct in acetaminophen hepatotoxicity