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C., Kao S

Sci Adv 7: eabg3750

Oxidative stress arises when there is an imbalance between oxidant generation and antioxidant capacity, leading to the accumulation of reactive oxygen species (ROS) and reactive nitrogen species (RNS), ultimately resulting in cellular injury and dysfunction 1

Hence, we suggest that NACs anti-relapse effect is mediated through modulation of the glutamatergic system, enhancing extinction learning specifically via activation of mGluR 2/3 receptors