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Indeed, a transgenic syn/amyloid/tau pathology mouse line (DLB-AD), established by crossing the 3xTg-AD [161] amyloid/tau line with the M83-h [216] mutant A53T syn line, demonstrated that syn pathology is capable of promoting A and tau accumulation [3]

The influence of the HPA axis on the immune response can occur through three mechanisms involving the influence of hormones of adrenocorticotropic origin, the influence of hypothalamic hormones, and the activity of pituitary hormones

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