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Standard treatment metformin, the oral contraceptive pill, spironolactone manages symptoms

When the body lacks adequate B12, it struggles to produce sufficient red blood cells, leading to decreased oxygen delivery to tissues and organs, resulting in fatigue, weakness, and lethargy

Both promote angiogenesis, but through different upstream pathways (VEGF-mediated for BPC-157, endothelial migration-mediated for TB-500), potentially producing additive vascularisation effects