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This project has been supported by grants from the Swiss National Science Foundation [CR20I3-146431, 31003A-176206 and 197942 to C.S

Oxidative stress can render tumor cells insensitive to anti-proliferative signals, apoptosis, and anchorage-independent growth, which alters tumor cell invasion and migration through epigenetic and metabolic mechanisms, further contributing to colorectal cancer development and progression (Ziczuk et al., 2020)