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10.1093/toxsci/kfg223 80 LawsS

Because the reaction consumes both nicotinamide and a methyl donor, changes in NNMT expression may influence the availability of metabolites associated with NAD turnover and methylation balance

Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers

[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Cumulative roles for Epstein-Barr virus, human endogenous retroviruses, and human herpes virus-6 in driving an inflammatory cascade underlying MS pathogenesis

In cancer (Table 1), CDO1 is usually silenced by promoter methylation and this is associated with poor prognosis, 70,74 implying that the shutting down of CDO1 expression favours cancer progression