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Biochemical and histological analyses were performed on the hippocampal and cortical tissue, assessing oxidative stress markers, antioxidant enzyme activity, and glial activation through spectrophotometric assays and immunohistochemistry

The highest prevalence of illegal methamphetamine use occurs in parts of Asia and Oceania, and in the United States, where racemic methamphetamine and dextromethamphetamine are classified as Schedule II controlled substances