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doi: 10.3389/fncel.2022.995084

258,259 In senescent cells, the mitochondrial fission increases, causing the increase of dysfunctional mitochondria

What those studies do and do not tell us These studies are small

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Pre-clinical VitC monotherapy studies A vast number of studies have shown encouraging anti-cancer activity of VitC at millimolar concentrations (~ 120 mM) in pre-clinical models of various cancer types [15]