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[] For example, NRF1 regulates key factors required to maintain mtDNA, including mitochondrial transcription factor A (TFAM) and mitochondrial transcription factor B2 (TFB2M)

Common reasons for deficiency include: Low intake particularly diets low in whole grains, legumes, leafy greens or animal products Gut health issues like low stomach acid, SIBO, coeliac disease, IBD, or other factors affecting absorption Medications such as the contraceptive pill, metformin or antacids, which can deplete B vitamins Chronic stress increases demand for certain b vitamins, including B5 and B6 Vegan or vegetarian diets higher risk of B12 deficiency, which can be corrected through supplementation Genetic reasons some mutations on certain genes can increase a persons need for B vitamins This is why I always recommend testing before supplementing

It also plays a role in detoxification processes within the body.

Treating male infertility Men with hypogonadism, a situation in which their testes cant produce enough testosterone

Theyll also ease you into eating solid foods