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The most commonly used DMARDs are: METHOTREXATE ( Non-Biologic ): it can be taken orally, has antiinflammatory effects and reduces the number of activated T cells and TNF- levels

That resulted in the buildup of A plaque aggregates as well as tau phosphorylation, causing neuronal loss 41,42

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Without adequate selenium, the antioxidant capacity of the glutathione system is severely compromised, leaving cells vulnerable to oxidative damage