The primary endpoint was to determine the change in CAT phlegm score at 12 weeks compared to the baseline
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Through these coordinated effects, they attenuate S aggregation, promote proteostatic clearance, preserve dopaminergic neuron integrity, and maintain blood brain barrier stability
Since increased -tubulin acetylation has been reported to interact with S and stabilises microtubules (Jensen et al., 2000), it could be possible that increased acetylated -tubulin stimulates S aggregations through its affinity to microtubules (Outeiro et al., 2007) and promotes cell death
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